nsg mice Search Results


90
Corning Life Sciences 50× nod-scid or nsg mice
50× Nod Scid Or Nsg Mice, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory un-irradiated immunodeficient nod.cgprkdcscidil2rgtm1wjl/szj (nsg) mice
Un Irradiated Immunodeficient Nod.Cgprkdcscidil2rgtm1wjl/Szj (Nsg) Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
Glaxo Smith nsg mice engrafted with human erythrocytes
Nsg Mice Engrafted With Human Erythrocytes, supplied by Glaxo Smith, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Jackson Laboratory raji xenograft tumor-bearing nsg mice
Raji Xenograft Tumor Bearing Nsg Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Jackson Laboratory nsg mice tm00702
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Nsg Mice Tm00702, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jackson Laboratory nod/scid/γc −/− (nsg) 12-week-old female mice
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Nod/Scid/γc −/− (Nsg) 12 Week Old Female Mice, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Helmholtz Zentrum fur Infektionsforschung GmbH non-obese diabetic scid gamma (nsg) mice
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Non Obese Diabetic Scid Gamma (Nsg) Mice, supplied by Helmholtz Zentrum fur Infektionsforschung GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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90
Jackson Laboratory immunocompromised nsg mice strain 005557
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Immunocompromised Nsg Mice Strain 005557, supplied by Jackson Laboratory, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Shanghai Model Organisms Center subcutaneous tumor-bearing male nsg mice
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Subcutaneous Tumor Bearing Male Nsg Mice, supplied by Shanghai Model Organisms Center, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/subcutaneous tumor-bearing male nsg mice/product/Shanghai Model Organisms Center
Average 90 stars, based on 1 article reviews
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90
Charles River Laboratories ncg
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Ncg, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ncg/product/Charles River Laboratories
Average 90 stars, based on 1 article reviews
ncg - by Bioz Stars, 2026-02
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90
Brehm GmbH hu-pbl-nsg-mhcnull humanized mouse
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Hu Pbl Nsg Mhcnull Humanized Mouse, supplied by Brehm GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hu-pbl-nsg-mhcnull humanized mouse/product/Brehm GmbH
Average 90 stars, based on 1 article reviews
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90
Charles River Laboratories nsg mice
a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour <t>TM01612</t> (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.
Nsg Mice, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nsg mice/product/Charles River Laboratories
Average 90 stars, based on 1 article reviews
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Image Search Results


a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour TM01612 (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.

Journal: Nature Communications

Article Title: Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

doi: 10.1038/s41467-020-17181-w

Figure Lengend Snippet: a , b NSG mice with subcutaneous implantation of melanoma PDX tumour TM00702 (Control, n = 10; High Gln, n = 9 biologically independent tumours) received control or high glutamine (High Gln) diet and tumours were measured twice weekly ( a ) and tumour weights post mortem are shown in b . c , d NSG mice with subcutaneous implantation of melanoma PDX tumour TM01612 (Control, n = 8; High Gln, n = 8 biologically independent tumours) received control or High Gln diet and tumours were measured twice weekly ( c ) and tumour weights post mortem are shown in d . e , f Glutamine concentration in PDX TM00702 in e and TM01612 in f from serum and tumours were measured ( n = 8 biological replicates). g Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were H&E stained. Scale bar = 100 μm. Arrows indicate regions of necrosis/apoptosis. h Cross-sections of PDX_TM00702 (left) and PDX_TM01612 (right) tumours were Ki67 stained (Control, n = 3; High Gln, n = 3). Scale bar = 100 μm. Data represent means and error bars are s.d. p value was calculated by t test (unpaired, two tailed) except in a , c by Mann–Whitney test (unpaired, two tailed). * p < 0.05, ** p < 0.01.

Article Snippet: For PDX studies, NSG mice were purchased from the Jackson Laboratory carrying the TM00702 or TM01612 tumours.

Techniques: Control, Concentration Assay, Staining, Two Tailed Test, MANN-WHITNEY

a Hierarchical clustering and heat map of differentially expressed genes (DEGs) in PDX_TM00702 tumours from control (Ctrl) or glutamine supplementation (Gln) mice groups ( n = 4, biological replicates). b Pathway enrichment analysis of all DEGs ( p < 0.05 and FDR < 0.05) in Gln versus Ctrl groups with fold change = ±1.5. c Pathway enrichment analysis of DEGs downregulated in Gln versus Ctrl groups with fold change ≥1.5, p < 0.05 and FDR < 0.05. d GSEA analysis in control (Ctrl) versus glutamine supplemented (Gln) tumours. e Pathway enrichment analysis of DEGs upregulated in Gln versus Ctrl groups with fold change <−1.5, p < 0.05 and FDR < 0.05. f GSEA analysis in control (Ctrl) versus glutamine supplemented (Gln) tumours. g , h Melanoma-associated oncogenes expression in PDX_TM00702 in g and PDX_TM01612 in h tumours verified by qPCR ( n = 3, biological replicates performed in triplicates). Data represent means and error bars are s.d. p value calculated by t test (unpaired, two tailed). Source data are provided as a Source data file.

Journal: Nature Communications

Article Title: Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth

doi: 10.1038/s41467-020-17181-w

Figure Lengend Snippet: a Hierarchical clustering and heat map of differentially expressed genes (DEGs) in PDX_TM00702 tumours from control (Ctrl) or glutamine supplementation (Gln) mice groups ( n = 4, biological replicates). b Pathway enrichment analysis of all DEGs ( p < 0.05 and FDR < 0.05) in Gln versus Ctrl groups with fold change = ±1.5. c Pathway enrichment analysis of DEGs downregulated in Gln versus Ctrl groups with fold change ≥1.5, p < 0.05 and FDR < 0.05. d GSEA analysis in control (Ctrl) versus glutamine supplemented (Gln) tumours. e Pathway enrichment analysis of DEGs upregulated in Gln versus Ctrl groups with fold change <−1.5, p < 0.05 and FDR < 0.05. f GSEA analysis in control (Ctrl) versus glutamine supplemented (Gln) tumours. g , h Melanoma-associated oncogenes expression in PDX_TM00702 in g and PDX_TM01612 in h tumours verified by qPCR ( n = 3, biological replicates performed in triplicates). Data represent means and error bars are s.d. p value calculated by t test (unpaired, two tailed). Source data are provided as a Source data file.

Article Snippet: For PDX studies, NSG mice were purchased from the Jackson Laboratory carrying the TM00702 or TM01612 tumours.

Techniques: Control, Expressing, Two Tailed Test